Various embodiments of a tracheal tube having a multifunctional lumen disposed in a tracheal tube wall are provided. Provided tracheal tubes include a ventilation lumen, through which bidirectional airflow may be established to and from a patient during operation, as well as a multifunctional lumen adapted to receive a variety of interchangeable medical devices. Embodiments of the provided tracheal tubes may provide for insertion or removal of a medical device from the multifunctional lumen without extubation of the tracheal tube from a patient.