MANUFACTURING OF MULTI-DOSE INJECTION READY DENDRITIC CELL VACCINES AND COMBINATION THERAPY FOR BLOCKING HER2 AND HER3

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专利权人:

CZERNIECKI; BRIAN J.

发明人:

CZERNIECKI, BRIAN J.,KOSKI, GARY K.

申请号：

CA2955445

公开号：

CA2955445A1

申请日:

2015.07.17

申请国别(地区):

CA

年份:

2016

代理人:

摘要：

The present invention relates to an FDA- approved injectable multi-dose antigen pulsed dendritic cell (DC) vaccine. In one embodiment, the activated antigen- loaded DC vaccine comprises an initial immunizing dose and multiple "booster" doses. The invention also provides a method of blocking both HER-2 and HER-3 as a treatment in causing permanent tumor senescence in HER-2 expressing breast cancers.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/