A moisture-resistant multi-phase orthopedic system including a moisture-impervious sleeve, a moldable splint including a covered resin- Impregnated substrate, an elongate wrap for retaining the splint on the limb, and a removable cast for application to the limb during subsequent treatment phase Including a cast body having interior side and exterior side and comprising a fabric having an open structure for providing enhanced moisture transfer away from the skin and a movable flap carried by the body overlying a part of the cast body to be applied to a treatment area of the limb, the flap adapted to cover and retain between the cast body and the flap the splint worn by the patient during the initial treatment phase in the same position as the location of the splint during the initial treatment phase. A method of immobilizing a limb in multiple treatment phases utilizing the orthopedic system.