您的位置: 首页 > 农业专利 > 详情页

SULFONATE HYDROXYÉTHYLIQUE D'UN INHIBITEUR DE PROTÉINE KINASE DÉPENDANT DE LA CYCLINE, FORME CRISTALLINE DE CELUI-CI ET LEUR PROCÉDÉ DE PRÉPARATION
专利权人:
Jiangsu Hengrui Medicine Co.; Ltd.
发明人:
申请号:
EP16746062.5
公开号:
EP3255046B1
申请日:
2016.01.12
申请国别(地区):
EP
年份:
2019
代理人:
摘要:
The present invention relates to a hydroxyethyl sulfonate of cyclin-dependent protein kinase inhibitor, a crystalline form thereof and a preparation method therefor. Specifically, the present invention relates to 6-acetyl-8-cyclopentyl-5-methyl-2-((5-(piperidin-4-yl)pyridin-2-yl)amino)pyrido[2,3-d] pyrimidin-7(8H)-one hydroxyethyl sulfonate (compound of formula (I)), a crystal type I thereof and a preparation method therefor. Crystal type I of the compound shown in formula (I) obtained by the present invention has good chemical stability and crystalline stability, and has low toxicity and residue with respect to the solvent used for crystallization. Therefore, the crystal type I can be used in clinical therapy better.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充