BICALHO, RODRIGO CARVALHO,GILBERT, ROBERT OWEN,MACHADO, VINICIUS,BICALHO, MARCELA
申请号:
CA2893072
公开号:
CA2893072A1
申请日:
2013.10.08
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
Provided are compositions and methods for use in prophylaxis of puerperal metritis and improving reproductive function of ruminants. The methods and compositions are for subcutaneous administration and are provided as veterinary compositions and as articles of manufacture. The veterinary composition can contain whole cells selected from whole cells of Escherichia coli (E. coli), Trueperella pyogenes (T. pyogenes), Fusobacterium necrophorum (F. necrophorum) and combinations thereof; and/or proteins selected from F. necrophorum leukotoxin (LKT), E. coli type 1 fimbrial adhesin (FimH), T. pyogenes pyolysin (PLO), and all combinations of the whole cells and the proteins.