The present invention provides an antibacterial resin which is used for coating on the surface of a substrate, or may be added to other resinous materials. The antibacterial resin comprises a resin-based group and an antibacterial molecule, wherein the antimicrobial molecule is obtained from at least one of hydrolysis reaction and condensation reaction of a reactive monomer containing amino siloxane functional group. In addition, the present invention also provides a method for producing the aforementioned antibacterial resin.本發明提供一種抗菌樹脂,用於塗覆於一基材的表面,或可添加於其他樹脂材料中,該抗菌樹脂包含一樹脂型基團,及一抗菌分子;其中,該抗菌分子是由含有氨基矽烷氧官能基團的反應單體經水解反應及縮合反應而得。此外,本發明亦提供一種前述抗菌樹脂的製作方法。