An endoscope (10) comprises: an observation optical system (50) including a prism (70), the observation optical system (50) being configured to receive an observed image; an image pickup device (100) attached to the prism (70), the image pickup device (100) being configured to convert the observed image taken by the observation optical system (50) into a video signal with a solid-state image pickup element (102); a drive circuit (80) electrically connected with the image pickup device (100); a light guide (90) configured to radiate a light from an illumination light source; a forceps opening (56); a frame (114) configured to surround a periphery of the image pickup device (100) and the prism (70) on three or more sides; and an insulative resin (112) which is accommodated in the frame (114).