您的位置: 首页 > 农业专利 > 详情页

FORME CRISTALLINE DE BISULFATE D'INHIBITEUR DE JAK ET SON PROCEDE DE PREPARATION
专利权人:
JIANGSU HENGRUI MEDICINE CO.; LTD.
发明人:
SUN, PIAOYANG,WU, GUAILI,GAO, XIAOHUI,CHEN, YONGJIANG,SHEN, LINGJIA
申请号:
CA2963581
公开号:
CA2963581A1
申请日:
2015.09.09
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
Provided is an I-type crystal of a JAK (Janus Kinase) inhibitor (3aR,5s,6aS)-N-(3-methoxyl-1,2,4-thiadiazole-5-yl)-5-(methyl(7H-pyrrolo[2,3-d]pyrimidine-4-yl)amino)hexahydrocyclopenta[c]pyrrole-2(1H)-formamide bisulfate represented by formula (I), and a preparation method therefor. The preparation method comprises crystallizing any crystal form of or amorphous compound solid of formula (I) in a single organic solvent to obtain the I-type crystal; this crystal has excellent crystal stability and chemical stability, and the crystal solvent used is low in toxicity and residues, making the compound better applicable to clinical treatment.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充