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EF44 Novel Enterococcus faecium specific bacteriophage EF44 and antibacterial composition comprising the same
专利权人:
주식회사 옵티팜
发明人:
연영은,김영주,김현일,박철세
申请号:
KR1020190169714
公开号:
KR1020200080162A
申请日:
2019.12.18
申请国别(地区):
KR
年份:
2020
代理人:
摘要:
The present invention comprises the step of administering a novel bacteriophage EF44 having a specific killing ability to Enterococcus faecium bacteria, an antibiotic composition comprising the bacteriophage, a composition for adding feed, a feed, a disinfectant or detergent, and the bacteriophage to an individual. The present invention relates to a method for preventing or treating infectious diseases caused by Enterococcus faecium bacteria. The bacteriophage EF44 of the present invention has the advantage of being highly specific to Enterococcus fasciitis bacteria, showing excellent lytic activity by infecting Enterococcus fasciitis bacteria, and being strong against physicochemical stimuli. . In addition, since the bacteriophage EF44 of the present invention does not infect other hosts other than bacteria such as humans, animals, plants, etc., it has the advantage of solving problems of antibiotic-resistant bacteria due to misuse of antibiotics, residual problems of antibiotics in food, and problems of a wide range of hosts. In addition, it is capable of killing the Enterococcus fascius bacteria resistant to vancomycin, and thus has the advantage of being able to solve infectious diseases of the vancomycin-resistant Enterococcus fasciitis bacteria or the vancomycin-resistant Enterococcus fasciitis bacteria. Therefore, the bacteriophage EF44 of the present invention can be used in various fields in the field of prevention or treatment of infectious diseases caused by Enterococcus faecium bacteria, antibiotic composition, composition for feed addition, feed, disinfectant, or detergent.본 발명은 엔테로코커스 패시움 균에 특이적인 사멸능을 갖는 신규 박테리오파지 EF44, 상기 박테리오파지를 포함하는 항생용 조성물, 사료 첨가용 조성물, 사료, 소독제 또는 세척제 및 상기 박테리오파지를 개체에 투여하는 단계를 포함하는 엔테로코커스 패시움 균에 의한 감염성 질병의 예방 또는 치료 방법에 관한 것이다. 본 발명의 박테리오파지 EF44는 기존의 항생제 등의 화학물질에 비해 엔테로코커스 패시움 균에 대한 특이성이 매우 높고, 엔테로코커스 패시움 균에 감염하여 탁월한 용균 활성을 나타내고 물리화학적 자극에 강하다는 장점을 가지고 있다. 또한 본 발명의 박테리오파지 EF44는 사람, 동물, 식물 등 세균 외의 다른 숙주에는 감염되지 않으므로, 항생제의 오남용으로 인한 항생제 내
来源网站:
中国工程科技知识中心
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