The present invention relates to a pharmaceutical composition for preventing and treating obesity which comprises the green tea (Camellia sinensis L.) seed husk extract or the fraction thereof as an active ingredient. The green tea seed husk extract exhibits a significant vasculogenesis suppressing effect and has been confirmed to be effective in reducing adipocytes and body weight, and thus the green tea seed husk extract can advantageously be used as an active ingredient in a composition for preventing and treating obesity, a health food for preventing and alleviating obesity, or a pharmaceutical composition for vasculogenesis suppression.