Apparatus for the evaluation of pain level and nociception during general anesthesia using electroencephalogram, plethysmographic impedance cardiography, variability of heart rate and the concentration or biophase of analgesics
Hospital Clínic de Barcelona;QUANTIUM MEDICAL S.L.
发明人:
JENSEN, Erik Weber,GAMBUS, Pedro Luis
申请号：
ES15869378
公开号：
ES2758552T3
申请日:
2015.12.17
申请国别(地区):
ES
年份:
2020
代理人:
摘要：
Means and methods for measuring pain and adapted for calculating the level of nociception during general anesthesia or sedation from data including electroencephalogram (EEG), facial electromyogram (EMG), heart rate variability (HRV) by electrocardiogram (ECG) and plethysmography by impedance cardiography (ICG). In a preferred embodiment of this invention the parameters derived from the EEG, the HRV, the plethysmographic curve and the analgetics concentrations are either combined into one index on a scale from 0 to 100, where a high number is associated with high probability of response to noxious stimuli, while a decreasing index is associated with decreasing probability of response to noxious stimuli. Zero (0) indicates extremely low probability of response to noxious stimuli. In an alternative embodiment, only features from the EEG and ECG will be used or only features from EEG, ECG and ICG, to define the fmal index.
