APPAREIL POUR L'ÉVALUATION DU NIVEAU DE DOULEUR ET DE NOCICEPTION AU COURS D'UNE ANESTHÉSIE GÉNÉRALE À L'AIDE D'UN ÉLECTROENCÉPHALOGRAMME, D'UNE CARDIOGRAPHIE D'IMPÉDANCE PLÉTHYSMOGRAPHIQUE, DE LA VARIABILITÉ DE LA FRÉQUENCE CARDIAQUE ET DE LA CONCENTRATION OU BIOPHASE DES ANALGÉSIQUES
Hospital Clínic de Barcelona;QUANTIUM MEDICAL S.L.;Jensen, Erik Weber
发明人:
JENSEN, Erik Weber,GAMBÚS, Pedro Luis
申请号：
EP15869378
公开号：
EP3232917A4
申请日:
2015.12.17
申请国别(地区):
EP
年份:
2018
代理人:
摘要：
Means and methods for measuring pain and adapted for calculating the level of nociception during general anesthesia or sedation from data including electroencephalogram (EEG), facial electromyogram (EMG), heart rate variability (HRV) by electrocardiogram (ECG) and plethysmography by impedance cardiography (ICG). In a preferred embodiment of this invention the parameters derived from the EEG, the HRV, the plethysmographic curve and the analgetics concentrations are either combined into one index on a scale from 0 to 100, where a high number is associated with high probability of response to noxious stimuli, while a decreasing index is associated with decreasing probability of response to noxious stimuli. Zero (0) indicates extremely low probability of response to noxious stimuli. In an alternative embodiment, only features from the EEG and ECG will be used or only features from EEG, ECG and ICG, to define the fmal index.
