AI-designed proteins tackle century-old problem — making snake antivenoms

AI 设计的蛇类抗蛇毒血清蛋白质

关键词：

来源：

nature

来源地址：

https://www.nature.com/articles/d41586-025-00133-z

资源所属：

马铃薯基因组设计育种

类型：

前沿资讯

语种：

英语

原文发布日期：

2025-01-17

摘要：

Researchers have used artificial intelligence (AI) to develop proteins that can block the deadly effects of snake venom. They used a protein-design program called RFdiffusion to design ‘mini-binder’ proteins that attach to key regions of venom toxins to neutralize them. Mice injected with what would be a lethal dose of the venom all survived when given these mini-binders 15 minutes later.