University of Groningen chemists produce new-to-nature enzyme containing boron

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格罗宁根大学科学家合成一种新的天然硼酸酶

关键词：

来源：

Eurek Alert

全文链接：

//agri.nais.net.cn/topic/downloadFile/ca463abf-321a-444e-8836-6fe2eb53efbf

来源地址：

https://www.eurekalert.org/news-releases/1043951

资源所属：

饲料用酶工程

类型：

前沿资讯

语种：

英语

原文发布日期：

2024-05-08

摘要：

Boronic acid has been used in organic chemistry for decades, even though it is not present in any organism. ‘It gives rise to different chemical reactions than those we find in nature,’ explains Gerard Roelfes, Professor of Biomolecular Chemistry & Catalysis at the University of Groningen. His group created an enzyme with boronic acid at its reactive centre and then used directed evolution to make it more selective and to improve its catalytic power. Furthermore, enzymatic reactions are more sustainable than classical chemical reactions, as they take place at low temperatures and without toxic solvents. The study was presented online in the journal Nature on 8 May.