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Rapid and cost-effective detection of perchlorate in water using paper-based analytical devices

使用纸基分析设备快速和经济高效地检测水中的高氯酸盐

关键词:
来源:
Desalination and Water Treatment 期刊
来源地址:
https://www.sciencedirect.com/science/article/pii/S1944398624014930
类型:
学术文献
语种:
英语
原文发布日期:
2023-12-20
摘要:
This study aimed to develop and evaluate the performance of a microfluidic paper-based device for measuring perchlorate levels in water samples. Smartphone-based digital imaging was integrated with microfluidic paper-based analytical device to establish a reliable colorimetric method for detecting perchlorate contamination. The results demonstrated successful quantitative estimation of perchlorate levels in water samples using a colorimetric assay based on the methylene blue-perchlorate reaction. Real-time, on-site colorimetric data were collected using a digital smartphone, and image processing methods were used to detect the occurrence of perchlorate in water samples from digital images. The developed approach yielded a broad linear response ranging from 4 to 12 μg/L (R2 = 0.97) for perchlorate detection, with a limit of detection of 3.41 μg/L and a limit of quantification of 10.34 μg/L. The findings underscore the effectiveness of colorimetric analysis and digital imaging for paper-based analytical devices. The limitations of this method include the capability to detect only a single analyte and the requirement for additional steps in image processing to obtain analytical results. Future developments should focus on designing devices for simultaneous detection of multiple contaminants and exploring automated methods of image analysis.
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