Copy Number Variation among Resistance Genes Analogues in Brassica napus

• 全文链接

甘蓝型油菜抗病基因同源序列拷贝数变异研究

关键词：

来源：

Genes

全文链接：

//agri.nais.net.cn/topic/downloadFile/82c202a3-29db-4030-8077-d785a60e513c

来源地址：

https://www.mdpi.com/2073-4425/13/11/2037

资源所属：

蔬菜育种专题

类型：

学术文献

语种：

英语

原文发布日期：

2022-11-04

摘要：

Copy number variations (CNVs) are defined as deletions, duplications and insertions among individuals of a species. There is growing evidence that CNV is a major factor underlining various autoimmune disorders and diseases in humans; however, in plants, especially oilseed crops, the role of CNVs in disease resistance is not well studied. Here, we investigate the genome-wide diversity and genetic properties of CNVs in resistance gene analogues (RGAs) across eight Brassica napus lines. A total of 1137 CNV events (704 deletions and 433 duplications) were detected across 563 RGAs. The results show CNVs are more likely to occur across clustered RGAs compared to singletons. In addition, 112 RGAs were linked to a blackleg resistance QTL, of which 25 were affected by CNV. Overall, we show that the presence and abundance of CNVs differ between lines, suggesting that in B. napus, the distribution of CNVs depends on genetic background. Our findings advance the understanding of CNV as an important type of genomic structural variation in B. napus and provide a resource to support breeding of advanced canola lines.