Building a Synthetic Cell Together

共同构建合成细胞

关键词：

来源：

Nature Communications

来源地址：

https://www.nature.com/articles/s44286-025-00263-1

资源所属：

马铃薯基因组设计育种

类型：

前沿资讯

语种：

英语

原文发布日期：

2025-08-14

摘要：

Synthetic cells (SynCells) are artificial constructs designed to mimic cellular functions, offering insights into fundamental biology, as well as promising impact in the fields of medicine, biotechnology, and bioengineering. Achieving a functional SynCell from the bottom up, i.e. by assembling it from molecular components, requires a global collaboration to overcome the many challenges of engineering and assembling life-like modules while addressing biosafety, equity, and ethical concerns in order to guide responsible innovation. Here, we highlight major scientific hurdles, such as the integration of functional modules by ensuring compatibility across diverse synthetic subsystems, and we propose strategies to advance the field.