Biohybrid volatile organic compound sensing system

• 全文链接

生物杂化体挥发性有机化合物传感系统

关键词：

来源：

IEEE National Aerospace and Electronics Conference

全文链接：

//agri.nais.net.cn/topic/downloadFile/31f73b54-0108-47e5-b2ac-a434bbc12cb0

来源地址：

https://ieeexplore.ieee.org/document/10670636

资源所属：

茶学研究专题

类型：

会议论文

语种：

英语

原文发布日期：

2024-09-18

摘要：

A biohybrid sensor is reported to integrate live insect antennae with micro electrode arrays. High resolution recording of voltage responses generated by olfactory sensory neurons (OSNs) were obtained in response to a panel of four volatile organic compounds (VOCs) at two concentrations, 20 parts per billion (ppb) and 20 parts per million (ppm). Biohybrid sensor lifetime was sustained by a novel micro fluidic platform with sensor responses acquired at 24 hours, 48 hours, 7 days, and 14 days post resection of antenna from the host. VOC identity was classified by providing OSN firing rate histograms as input into a multilayer perceptron artificial neural network (MLP ANN). Biohybrid sensor response was found to be affected by anatomical location and VOC identity and thus influenced classification accuracies. Significant classification accuracies were achieved at the 24-hour and 14-day timepoints. Toluene at the 14-day timepoint elicited a unique response resulting in 100% classification at the distal anatomical location. We believe this works provides a framework for utilizing biohybrid sensing systems for VOC detection and identification.