Escherichia coli with a 57-codon genetic code
具有 57 密码子遗传密码的大肠杆菌
- 关键词:
- 来源:
- Science
- 类型:
- 学术文献
- 语种:
- 英语
- 原文发布日期:
- 2025-07-31
- 摘要:
- The near-universal genetic code uses 64 codons to encode the 20 canonical amino acids and protein synthesis. Here we designed and generated Escherichia coli with a 4 Mb synthetic genome in which we replaced known occurrences of six sense codons and a stop codon with synonymous codons. The resulting organism, Syn57, uses 55 codons to encode the 20 canonical amino acids.
- 所属专题:
- 177