Disclosed herein is a composite material for guided tissue regeneration (GTR). The composite material includes a substrate, a plurality of calcium salt particles and a hydrophilic polymeric coating layer. The substrate includes a plurality of biodegradable fibers interlaced with each other, and whereby pluralities of interstices are formed in the substrate. The calcium salt particles are dispersed in the composite. The hydrophilic polymer coating layer is adhered to at least a portion of the surface of the biodegradable fibers such that the composite material exhibits hydrophilicity. A method for manufacturing the composite material is disclosed as well.在此揭露一種具抑菌性之引導組織再生複合材料,其中包含一基材、複數鈣鹽顆粒及一親水性高分子塗層。基材包含鈣鹽顆粒且彼此交錯之生物可降解聚合物纖維,並使基材形成多孔質結構。鈣鹽顆粒分佈在基材內。親水性高分子層附著在生物可降解聚合物纖維的至少一部分表面,使引導組織再生之複合材料為親水性。在此亦揭露一種引導組織再生之複合材料的製造方法。100‧‧‧方法110、120、130‧‧‧步驟
