Laurent Pierre Paul DEBIEN,Jaroslaw KALISIAK,Kenneth V. LAWSON,Manmohan Reddy LELETI,Erick Allen LINDSEY,Dillon Harding MILES,Eric NEWCOMB,Jay Patrick POWERS,Brandon Reid ROSEN,Ehesan Ul SHARIF
申请号:
US16338975
公开号:
US20200222441A1
申请日:
2017.10.02
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Compounds that modulate the conversion of AMP to adenosine by 5′;-nucleotidase, ecto, and compositions containing the compounds and methods for synthesizing the compounds, are described herein. The use of such compounds and compositions for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders, that are mediated by 5′;-nucleotidase, ecto is also provided.