주식회사 엔지켐생명과학;KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY;한국생명공학연구원;ENZYCHEM LIFESCIENCES CORPORATION
发明人:
KIM, Jae Wha,김재화,HAN, Yong-Hae,한용해,SOHN, Ki Young,손기영,OH, Sei-Ryang,오세량,AHN, Kyung Seop,안경섭,KANG, Ho Bum,강호범,YOO, Jae Mine,유재민,LEE, Tae-Suk,이태석,KANG, JongKoo,강종구,KIM, Hye Kyung,김혜경,YOOK, Jin Soo,육진수
申请号：
KRKR2014/008229
公开号：
WO2015/034247A1
申请日:
2014.09.03
申请国别(地区):
KR
年份:
2015
代理人:
摘要：
The present invention relates to a pharmaceutical composition, functional health food composition, quasi-drug composition, and cosmetic composition containing a monoacetyldiacylglycerol compound as an active ingredient for preventing or treating atopic dermatitis. The monoacetyldiacylglycerol compound of the present invention has an excellent effect of suppressing IL-4 and IgE secretion, thereby overcoming side effects of an atopic dermatitis treatment agent currently in use, having no toxicity, and exhibiting an excellent treatment effect, and thus can be useful as a composition for preventing, treating, and ameliorating atopic dermatitis.L'invention concerne une composition pharmaceutique, une composition alimentaire fonctionnelle relevant du domaine de la santé, une composition quasi-pharmacologique, et une composition cosmétique contenant un composé de monoacétyldiacylglycérol comme principe actif pour prévenir ou traiter la dermatite atopique. Le composé de monoacétyldiacylglycérol selon l'invention supprime efficacement la sécrétion des IL-4 et des IgE et permet ainsi d'éviter les effets secondaires d'un agent de traitement de la dermatite atopique actuellement utilisé, il ne présente aucune toxicité, a une efficacité thérapeutique excellente et peut donc être utilisé comme composition pour prévenir, traiter et améliorer la dermatite atopique.본 발명은 모노아세틸디아실글리세롤 화합물을 유효성분으로 함유하는, 아토피 피부염의 예방, 치료 또는 개선용 약학적 조성물, 건강기능식품 조성물, 의약외품 조성물 및 화장료 조성물에 관한 것이다. 본 발명의 모노아세틸디아실글리세롤 화합물은 IL-4 및 IgE의 분비를 억제하는 효과가 우수하므로, 현재 사용되는 아토피 피부염 치료제의 부작용을 극복하고, 독성이 없으면서 치료효과가 탁월한 화합물로서 아토피 피부염 예방, 치료 및 개선용 조성물로 유용하게 사용될 수 있다.
