The system of the invention involves monitoring and controlling in a sterilizable environment the peeling of a cover from a tub sealed by the cover. The system employs a platform having a fiducial source locating structure for holding the tub, a cover removal station disposed to engage with the cover and to peel the cover from the tub, a light source disposed to illuminate a portion of the platform proximate the cover removal station, a light sensor sensitive to light from the light source and disposed to preferentially collect and measure light diffusely reflected from the illuminated portion of the platform, and a controller with software to operate the system. An associated method for monitoring and controlling the peeling of the cover involves moving a peeled portion of the cover into a predetermined peeling monitor zone within the illuminated portion of the platform, and measuring an intensity of light from the light source diffusely reflected specifically from the peeling monitor zone. The positioning of the elements of the system and the peeling monitor zone allow measured light intensity to be employed as a control measure for the peeling process. The container assembly for holding nested pharmaceutical container parts comprises a bottom, a top lip that provides a horizontal top sealing surface that has a peripheral outline, and sidewalls located between the bottom and the top lip, a peelable container cover consisting of a sheet of flexible material sealed to the sealing surface of the top lip of the rectangular container to seal the contents of the container, and a cover removal fixture on the container cover.本發明的系統涉及在可消毒的環境中監控及控制從由蓋密封的桶剝離該蓋；該系統提供：具有基準源定位結構以保持該桶的平台；蓋移除站，設置以與該蓋接合並從該桶剝離該蓋；光源，設置以照射靠近蓋移除站的平台的一部分；光感測器，可感測來自光源的光，且設置以優先收集及測量從平台的被照射部分漫反射的光；及具有軟體的控制器，用以操作該系統。一種用於監控及控制該蓋的剝離的相關方法涉及移動該蓋之被剝離的部分進入平台之被照射部分內之一預定剝離監控區域、及測量來自光源(尤其來自剝離監控區域)的漫反射的光強度。該系統的元件定位及該剝離監控區域允許測量的光強度作為剝離過程用的控制測量。用於保持套疊的藥物容器部件的容器組件包括：底部、頂部唇緣，提供具有外圍輪廓的水平頂部密封表面、側壁，位於底部與頂部唇緣之間、和可剝離的容器蓋，由密封
