Compositions for the treatment of shock autodigestion multi organ failure intestinal ischemia or intestinal hypoperfusion are provided. In some embodiments compositions disclosed herein comprise tranexamic acid PEG glucose and one or more electrolytes. In some embodiments the PEG is PEG 3350. In some embodiments compositions disclosed herein comprise tranexamic acid PEG glucose and one or more electrolytes. In some embodiments the PEG is PEG 3350. In certain embodiments compositions disclosed herein comprise a non colonic cleansing amount of PEG 3350.
