The present invention relates to a skin protecting composition having antioxidant activity comprising an epidermal growth factor (EGF) and placenta, and the purpose of the present invention is to provide a skin protecting composition having antioxidant activity comprising an EGF and placenta, the skin protecting composition which prepares mixtures of water-soluble skin agents, viscosity and hardness adjusting agents, UV absorbers, pigments, moisturizers, cleansers, preservatives, electrical materials, or the like by comprising the EGF, placenta, Argireline, collagen, and ingredients of herb medicines and oriental medicines such as ginseng extract, leaven, Licorice, soybean extract, and adenosine, thereby not only increasing the stability of EGF itself, but also further increasing the permeation of the EGF and placenta, Argireline, collagen, and oriental medicine ingredients into the skin and the body. The present invention provides effects that the stability of EGF itself can be increased by comprising ingredients of herb medicines and oriental medicines such as the ginseng extract, leaven, Licorice, soybean extract, and adenosine, besides the EGF, placenta, and collagen, and the effects can be maximized by stably permeating the EGF and placenta, Argireline, collagen, and oriental medicine ingredients into the skin at high concentrations without the stimulation to the skin. The skin protecting composition having antioxidant activity comprising the EGF and placenta according to the present invention is prepared by mixing an oriental and herb medicine extract comprised of ginseng, Chinese dioscorea, licorice, soybean, and cornus fruit with the EGF, human placenta, Argireline, Spirulina (Vitamin B-12), and collagen. The skin protecting composition comprises the EGF, human placenta, Argireline, Spirulina (Vitamin B-12), and collagen in amounts of 80 to 82 wt.% with respect to the total composition weight. The skin protecting composition comprises the oriental and herb m