The Regents of the University of Colorado; A Body Corporate
发明人:
Gill, Ryan T.,Garst, Andrew
申请号:
AU2018271257
公开号:
AU2018271257A1
申请日:
2018.11.27
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
#$%^&*AU2018271257A120181213.pdf#####ABSTRACT Described herein are methods and vectors for rational, multiplexed manipulation of chromosomes within open reading frames (e.g., in protein libraries) or any segment of a chromosome in a cell or population of cells, in which various CRISPR systems are used. See Fig. 1IB.WO 2015/123339 PCT/US2015/015476 13/19 11B ............. a Tamet enMe Mulitplexed Unedited ceB' Target Gene lbrarydet Figure 11, continued