Amy M. Elder;Francois Soucy;Sian Griffiths;Shomir Ghosh;Prakash Raman;Kevin Sprott;Qing Ye
发明人:
Amy M. Elder,Shomir Ghosh,Sian Griffiths,Prakash Raman,Francois Soucy,Kevin Sprott,Qing Ye
申请号:
US13269697
公开号:
US20120208818A1
申请日:
2011.10.10
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention provides compounds of general formula I:or a pharmaceutically acceptable salt thereof, wherein X, n, Y, and R1 are defined generally and in subsets herein. Compounds of the invention are inhibitors of CCR2 and accordingly are useful for the treatment of a variety of inflammatory, allergic, and autoimmune diseases, disorders, or conditions.