PROBLEM TO BE SOLVED: To provide pharmaceuticals having effectiveness for osteonecrosis prevention and/or therapy or osteonecrosis advance suppression.SOLUTION: There are provided pharmaceuticals for osteonecrosis prevention and/or therapy or osteonecrosis advance suppression, containing a compound represented by formula (I) (R1 represents H or hydroxy) or a salt thereof, or a hydrate or solvate thereof as an active ingredient.COPYRIGHT: (C)2012,JPO&INPIT【課題】骨壊死の予防及び/又は治療、あるいは骨壊死の進展抑制に有効性を有する医薬を提供する。【解決手段】式(I)(R1は水素原子又は水酸基を表す)で示される化合物若しくはその塩、又はそれらの水和物若しくは溶媒和物を有効成分として含む骨壊死の予防及び/又は治療、あるいは骨壊死の進展抑制のための医薬。【選択図】なし