Mark K. Slifka,Shirley Villadiego,Erika Hammarlund,Paul Yoshihara
申请号:
US14269708
公开号:
US20140242115A1
申请日:
2014.05.05
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present disclosure provides methods for producing a vaccine composition containing a pathogen that is rendered noninfectious by exposure to hydrogen peroxide. The methods disclosed herein are suitable for the preparation of vaccines for a wide variety of pathogens, including viruses, bacteria and parasites. The disclosure also provides vaccine compositions (medicaments) containing a pathogen inactivated by exposure to hydrogen peroxide. Methods for eliciting an immune response in a subject by administering vaccine compositions containing a hydrogen peroxide inactivated pathogen are also provided.