Henri Lichenstein,Neil Beeharry,Sean Landrette,Sophia Gayle,Jeff Grotzke,Marylens Hernandez,Peter R. Young,Jonathan M. Rothberg
申请号:
US16782508
公开号:
US20200253979A1
申请日:
2020.02.05
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The disclosure provides methods for treating cancer, including but not limited to, hematopoietic and lung cancers, using the HSP90 inhibitor, MPC-0767, as monotherapy and in combination therapy with additional active agents, including but not limited to, inhibitors of Bcl-2, EZH2 inhibitors, Ras/Raf/MEK/ERK pathway inhibitors, checkpoint inhibitors, DNMT inhibitors, ATO and chemotherapeutic agents. The disclosure also provides related compositions and methods of use.