Fondazione Istituto Italiano Di Tecnologia;Universita Degli Studi Di Urbino;Università degli Studi di Parma;The Regents of the University of California
发明人:
申请号：
EP12851203.5
公开号：
EP2782567B1
申请日:
2012.11.21
申请国别(地区):
EP
年份:
2017
代理人:
摘要：
The present invention provides compounds and pharmaceutical compositions for inhibiting N-acylethanolamine acid amidase (NAAA). Inhibition of NAAA is contemplated as a method to sustain the levels of palmitoylethanolamide (PEA) and oleylethanolamide (OEA), two substrates of NAAA, in conditions characterized by reduced concentrations of PEA and OEA. The invention also provides methods for treating inflammatory diseases and pain, and other disorders in which decreased levels of PEA and OEA are associated with the disorder.
