Beauglehole, Anthony,Thompson, Robert,Rieger, Jayson,Schmidtmann, Frank
申请号：
AU2012258401
公开号：
AU2012258401A1
申请日:
2012.11.27
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
#$%^&*AU2012258401A120121220.pdf#####SUBSTITUTED 4-{3-[6-AMINO-9-(3, 4-DIHYDROXY-TETRAHYDRO-FURAN-2-YL)9H-PURIN-2-YL]-PROP-2-YNYL}-PIPERIDINE-1-CARBOXYLIC ACID ESTERS AS A2AR AGONISTS ABSTRACT The present invention provides substituted 4-{3-[6-amino-9-(3,4-dihydroxy-tetrahydrofuran-2-yl)-9H-purin-2-yl]-prop-2-ynyl}-piperidine-l-carboxylic acid esters and pharmaceutical compositions containg the same that are selective agonists of A2A adenosine receptors (ARs). These compounds and compositions are useful as pharmaceutical agents.
