The Board of Regents of the University of Texas System
发明人:
Christopher C. Capelli,Phillip C. Phan,Allen W. Burton
申请号:
US15585980
公开号:
US10420720B2
申请日:
2017.05.03
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present invention provides methods for reducing pain in a subject in need of such pain reduction by delivering, e.g., intrathecally or epidurally, a volatile anesthetic dissolved in a solution comprising an extractive solvent, e.g., DMSO or NMP, in an amount effective to reduce pain. Chronic or acute pain may be treated, or the anesthetic may be delivered as a regional anesthesia to a subject to anesthetize a portion the subject prior to a surgery. In certain embodiments, isoflurane, halothane, enflurane, sevoflurane, desflurane, methoxyflurane, or mixtures thereof may be used. Dosing regimens including a one-time administration, continuous and/or periodic administration are contemplated.