Ricky D. Gaston;Subhash P. Khanapure;Ramani R. Ranatunge;Joseph D. Schroeder;Cheri A. Stevenso;L. Gordon Letts;Maiko Ezawa;Xinqin Fang;Richard A. Earl;David S. Garvey;Stewart K. Richardson;Chia-En Lin
发明人:
Richard A. Earl,Maiko Ezawa,Xinqin Fang,David S. Garvey,Ricky D. Gaston,Subhash P. Khanapure,L. Gordon Letts,Chia-En Lin,Ramani R. Ranatunge,Stewart K. Richardson,Joseph D. Schroeder,Cheri A. Stevenso
申请号：
US12980077
公开号：
US08222277B2
申请日:
2010.12.28
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The invention also provides methods for treating inflammation, pain and fever； for treating gastrointestinal disorders； for facilitating wound healing； for treating and/or preventing gastrointestinal, renal and/or respiratory toxicities resulting from the use of nonsteroidal antiinflammatory compounds； for treating inflammatory disease states and/or disorders； and for treating and/or preventing ophthalmic diseases and/or disorders comprising administration of novel compositions comprising at least one nitrosated NSAID, and, optionally, at least one compound that donates, transfers or releases nitric oxide, elevates endogenous levels of endothelium-derived relaxing factor, stimulates endogenous synthesis of nitric oxide or is a substrate for nitric oxide synthase and/or at least one therapeutic agent.
