A system for health and wellness mobile management comprises a database operable to store a health and wellness data record associated with a patient/data owner, a content management system adapted to strictly control access to the health and wellness data record stored in the database according to access rules set by the patient, a web interface adapted to interface with information requesters submitting requests for access to the health and wellness data record via a web application, an external connect interface adapted to interface with external systems and applications for receiving health and wellness data associated with the patient, a prescription interface adapted to receive a pharmaceutical prescription for the patient submitted by a healthcare provider, and a handheld physiological parameter measurement device adapted to wirelessly communicate with a computing device executing the web application.