In a tri-electrode electrochemical system, a metallic biomedical implant that is electrically conductive is used as a working electrode and an acidic solution mixed with a biopolymer and antibiotic is used as an electrolyte of the tri-electrode electrochemical system. The temperature of the electrolyte is a fixed value between 25 DEG C and 75 DEG C. A constant potential is set with respect to a reference electrode of the tri-electrode electrochemical system. The constant potential is a fixed value between -0.5 and -3.0 volts. Electrochemical deposition is carried out accordingly to form a composite antibacterium coating layer of the biopolymer and the antibiotics on a surface of the biochemical implant material. The working electrode on which the deposition of the composite antibacterium coating layer has been completed is taken out to be air dried at 25 DEG C. The method of the present invention specifically increases medicine carrying amount per unit area for antibiotic and extends the release time of the antibiotic. Furthermore, a biomedical implant material manufactured with the present invention shows magnificent cell adhesion rate, proliferation, and differentiation.在一三極電化學系統中,以具導電性之金屬生醫植入材為工作電極,以混合生物高分子和抗生素之酸性溶液做為該三極電化學系統之電解液,電解液溫度為25℃至75℃之間的一個固定值;以相對於該三極電化學系統之參考電極設定一恆定電位,該恆定電位為介於-0.5~-3.0伏特之間的一個固定值;據此進行電化學沈積,於該生醫植入材的表面形成一生物高分子與抗生素複合抗菌鍍層;將完成複合抗菌鍍層沈積的工作電極取出,於25℃陰乾。本發明方法具體的提昇了單位面積的抗生素載藥量,並延長了抗生素的釋放時間。此外,以本發明方法所製出之生醫植入材亦具有顯著的細胞貼附率、增值和分化。