Glenn R. Larsen;Ravindra Kumar;Gray Shaw;Dale Cumming;Dianne S. Sako;Geertruida M. Veldman;Xiao-Jia Chang
发明人:
Glenn R. Larsen,Dianne S. Sako,Xiao-Jia Chang,Geertruida M. Veldman,Dale Cumming,Ravindra Kumar,Gray Shaw
申请号：
US12167705
公开号：
US08232252B2
申请日:
2008.07.03
申请国别(地区):
US
年份:
2012
代理人:
摘要：
A novel P-selectin ligand glycoprotein is disclosed, comprising the amino acid sequence set forth in SEQ ID NO:2 or by the amino acid sequence set forth in SEQ ID NO:4. DNA sequences encoding the P-selectin ligand protein are also disclosed, along with vectors, host cells, and methods of making the P-selectin ligand protein. Pharmaceutical compositions containing the P-selectin ligand protein and methods of treating inflammatory disease states characterized by P-selectin- and E-selectin-mediated intercellular adhesion are also disclosed.
