PARK, Hyun Sook,박현숙,LEE, Sun Ray,이순례,PARK, Jang Mi,박장미,MO, Hyun Jung,모현정,GO, Eun Jin,고은진
申请号：
KRKR2014/001977
公开号：
WO2015/133668A1
申请日:
2014.03.11
申请国别(地区):
KR
年份:
2015
代理人:
摘要：
The present invention relates to a pharmaceutical composition for treating or preventing immune-related diseases, containing, as an active ingredient, a protein having a size of 5kDa to 1,000kDa, extracted from mesenchymal stem cells. Further, the present invention relates to a functional health food for alleviating, ameliorating, or preventing immune-related diseases, containing, as an active ingredient, a protein having a size of 5kDa to 1,000kDa, extracted from mesenchymal stem cells. Furthermore, the present invention relates to a cosmetic composition for alleviating, ameliorating, or preventing immune-related diseases, containing, as an active ingredient, a protein having a size of 5kDa to 1,000kDa, extracted from mesenchymal stem cells. Furthermore, the present invention relates to a method for preparing a mesenchymal stem cell-derived protein having immune response inhibitory activity, the method comprising: a step of extracting proteins from mesenchymal stem cells； and a step of classifying the proteins according to size to obtain a protein having a size of 5kDa to 1,000kDa. The protein having a size of 5kDa to 1,000kDa, extracted from mesenchymal stem cells, according to the present invention, effectively suppresses an immune response, and thus can be used for various immune-related diseases associated with the immune response.La présente invention concerne une composition pharmaceutique pour traiter ou prévenir des maladies immunitaires, contenant, en tant qu'ingrédient actif, une protéine de taille comprise entre 5 kDa et 1 000 kDa, extraite de cellules souches mésenchymateuses. De plus, la présente invention concerne un aliment fonctionnel pour atténuer, améliorer ou prévenir des maladies immunitaires, contenant, en tant qu'ingrédient actif, une protéine de taille comprise entre 5 kDa et 1 000 kDa, extraite de cellules souches mésenchymateuses. En outre, la présente invention concerne une composition cosmétique pour soulager, améliorer ou prévenir des ma
