A system and method are disclosed for obtaining pointing directions for every channel of a collimator which can then be used during the image reconstruction process to more accurately estimate the direction from which radiation has been received. The disclosed system and method provide for photographic measurement and analysis of individual collimator channel to determine the pointing directions for every channel in the collimator. This information is obtained by photographing the front and back sides of the collimator, and analyzing the digital image data to obtain the pointing angle of each channel. The resulting information, referred to as a “vector map” is included in the firmware of the collimator so that it can be called on during the projection and back-projection steps of the algorithm.
