Bert L. Semler,Richard Virgen-Slane,Janet M. Rozovics,Paul D. Gershon
申请号:
US15073037
公开号:
US20160243149A1
申请日:
2016.03.17
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Anti-viral therapeutics for use in viral targets having VPg unlinkase activity, including the broad class of picornaviruses, and therapeutic methods directed at suppression of such activity are provided. Such anti-viral therapies for use against human rhinovirus, for example, are particularly desirable as they would lessen both the severity and duration of upper respiratory distress in both normal and asthmatic individuals. Assays and purification protocols for detecting and purifying VPg unlinkase are also provided.