Methods of managing graft versus host disease (GvHD) using indole carboxyaldehydes or derivatives thereof

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专利权人:

Emory University

发明人:

Kalman Daniel,Waller Edmund K.,Giver Cynthia R.,Swimm Alyson,Rangaraju Sravanti

申请号：

US201615268577

公开号：

US10154989(B2)

申请日:

2016.09.17

申请国别(地区):

美国

年份:

2018

代理人:

Emory Patent Group

摘要：

In certain embodiments, this disclosure relates to methods of treating or preventing HvGD comprising administering an effective amount of indole-2-carboxyaldehyde, indole-3-carboxyaldehyde, or derivative to a subject in need thereof. In certain embodiments, this disclosure relates to methods of treating a subject with a hematological malignancy or other cancer comprising transplanting allogenic bone marrow or stem cells in combination with administering an effective amount of an indole-2-carboxyaldehyde, indole-3-carboxyaldehyde, or derivative thereof to a subject in need thereof.

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中国工程科技知识中心

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