Northeastern Univ.;Northeastern University Center for Research Innovation
发明人:
Thibault Colombani,Sidi A. Bencherif
申请号：
US17322054
公开号：
US20210353743A1
申请日:
2021.05.17
申请国别(地区):
US
年份:
2021
代理人:
摘要：
Disclosed are compositions and methods for preventing an infection, such as COVID-19 infection, comprising administering to the subject an oxygen-generating cryogel, wherein the oxygen-generating cryogel comprises an antigen, a chemoattractant for immune cells, an adjuvant, such as toll-like receptor 9 (TLR9) ligand, and an oxygen-producing compound. Described herein are methods of modulating the immune system in a subject, comprising administering an effective amount of the vaccine described herein to the subject, thereby modulating the immune system in the subject.
