THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUC. ON BEHALF OF THE UNIVERSITY OF NEVADA; LA
发明人:
SCHILLER, MARTIN R.,STRONG, CHRISTY L.
申请号：
CA2981509
公开号：
CA2981509A1
申请日:
2016.03.30
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
Disclosed herein, are compositions and methods for the treatment of human immunodeficiency virus infection. The compositions comprise engineered transcription activator like effector nucleases (TALENs) comprising a TALE DNA binding domain flanked by two spacer sequences, and a Fokl nuclease catalytic domain. Also, described herein, are methods of using TALENs to cleave nucleic acids and methods of administering the TALENs to subjects at risk for or having an HIV infection.
