Hydroxy amide Derivatives of pyrimidine Compounds, inhibitors of Protein deacetylase HDAC6 Pharmaceutical composition; Combination; Pharmaceutical; Methods of use for the treatment of a proliferative disease or cancer; a Kit
YU NAN,VAN DUZER, JOHN H.,MAZITSCHEK, RALPH,DING, YANBING,CAO, YUN,LIU YONG
申请号:
CL2013001381
公开号:
CL2013001381A1
申请日:
2013.05.15
申请国别(地区):
CL
年份:
2014
代理人:
摘要:
The present invention relates to novel pyrimidine hydroxy amide compounds, and the use of such compounds in the inhibition of HDAC6 and in the treatment of various diseases, disorders or conditions related to HDAC6.Compuestos derivados de hidroxi-amida-pirimidina, inhibidores de la proteína deacetilasa, selectivamente HDAC6; composición farmacéutica; útiles para el tratamiento del cáncer o enfermedad proliferativa, tales como cáncer de pulmón, colon, mama, próstata, hígado, cerebro, riñón, ovario, entre otros.