BYSTROM, STYRBJORN,HARALDSSON, MARTIN,JOHANSSON, LARS,TEJBRANT, JAN
申请号：
NZ58578709
公开号：
NZ585787A
申请日:
2009.01.16
申请国别(地区):
NZ
年份:
2012
代理人:
摘要：
The disclosure relates to isoxazole derivative compounds of formula (I), and pharmaceutically acceptable salts, solvates, hydrates, geometrical isomers, tautomers, optical isomers or N-oxides thereof, which are modulators of 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1). The disclosure also relates to pharmaceutical compositions comprising these compounds and to the use of these compounds in the preparation of a medicament for the treatment of glaucoma.
