A prescription management system and method enables users to create and manage seed treatment prescriptions and to automatically build a treatment mixture based on a designated treatment prescription. The prescription management system includes a supply system with access to a plurality of individual seed treatment products and a controller for actuating the supply system to transfer portions of the treatment products to a hopper tank according to the designated treatment prescription. The products are combined in the hopper tank to form the treatment mixture, which is then applied to a quantity of seeds.