Franz Dürrenberger,Michael Burgert,Susanna Burckhardt,Wilm Buhr,Aris Kalogerakis,Stefan Reim,Vania Manolova,Susan Boyce,Christopher John Yarnold,Paula Pena,Jon Shepherd,Cristina Lecci,Richard Jarjes-P
申请号：
US15769148
公开号：
US20180319783A1
申请日:
2016.10.21
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The invention relates to novel compounds of the general formula (A-I), with Het-2 being an optionally substituted bicyclic heteroaryl of the formula (AA) pharmaceutical compositions comprising them and the use thereof as medicaments, in particular for the use as ferroportin inhibitors, more particularly for the use in the prophylaxis and/or treatment of diseases caused by a lack of hepcidin or iron metabolism disorders, such as particularly iron overload states such as in particular thalassemia and hemochromatosis.
