#$%^&*AU2017100105A420170309.pdf#####ABSTRACT This invention provides a method of treating lung cancer including administering a therapeutically effective amount of a compound of 0089-0022formula I to a subject in need thereof. The compound activates pyruvate kinase M2 isoform (PKM2) to treat the lung cancer. In one example, the lung cancer is Non-Small Cell Lung Cancer (NSCLC). N- -S-NH formula I <;DocRef#00179451-YW>; 14