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Synthesis of free radical polymerizable ethylenically unsaturated poloxamers and poloxamines
专利权人:
Bausch & Lomb Incorporated
发明人:
Alok Kumar Awasthi,Jay F. Kunzler,Ganugapati Satyanarayana,Satheesha Rai Nooji
申请号:
US14308229
公开号:
US09309357B2
申请日:
2014.06.18
申请国别(地区):
US
年份:
2016
代理人:
摘要:
A new synthetic method of forming free radical polymerizable end terminal functionalized poloxamers and poloxamines in commercial scale batches which uses a binary system of inhibitors to eliminate the formation of high molecular weight impurities. It has also been surprisingly discovered that the inorganic impurities formed during the commercial scale synthetic process are removed by the use of resin materials.
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