ANTICORPS ANTI-MUC16 ET LEURS PROCEDES D'UTILISATION

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专利权人:

MEMORIAL SLOAN-KETTERING CANCER CENTER

发明人:

SPRIGGS, DAVID,THAPI, DHARMARAO

申请号：

CA2793753

公开号：

CA2793753C

申请日:

2011.03.25

申请国别(地区):

CA

年份:

2018

代理人:

摘要：

The invention provides antibodies, and antigen-binding fragments thereof, that specifically bind to a polypeptide, or antigenic portion thereof, wherein the polypeptide is selected from a) MUC16 ectodomain polypeptide, b) MUC16 cytoplasmic domain polypeptide, and c) MUC16 extracellular domain polypeptide that contains a cysteine loop polypeptide. The invention's antibodies and compositions containing them are useful in diagnostic and therapeutic applications for diseases in which MUC16 is overexpressed, such as cancer.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/